In case of cervical and upper thoracic spinal cord injuries, refractory orthostatic hypotension may result from unmeet parasympathetic system influences and sympathetic system impairment due to the diffuse destruction of the sympathetic innervation of the body and the preservation of parasympathetic cranial innervation in certain patients. Pharmacological treatments include mineralocorticoids and adrenergic agents, while non-pharmacological methods such as abdominal pads and compression devices can be used. Herein, we report a 21-year-old male case of refractory orthostatic hypotension following a fifth cervical vertebra compression fracture. The case was treated with mineralocorticoid therapy in conjunction with electrical stimulation to the quadriceps and tibialis anterior muscles. The results of the treatment and treatment strategies of orthostatic hypotension are discussed in the light of literature data. Keywords: Cervical spinal cord injury; orthostatic hypotension; treatment. Servikal ve ust torakal spinal kord yaralanmalarinda sempatik sistemin vucuttaki yaygin inervasyonunun zarar gormesi ve parasempatik kraniyal inervasyonun korunmasi nedeniyle karsilanamayan parasempatik sistem etkisi ve sempatik sistemin bozuklugu, bazi hastalarda direncli ortostatik hipotansiyona neden olabilmektedir. Medikal tedavi mineralokortikoidler ve adrenerjik ajanlardan olusmakla birlikte, abdominal yastik ve kompresyon cihazi gibi farmakolojik olmayan yontemler de kullanilabilmektedir. Bu yazida, besinci servikal vertebra kompresyon kirigi sonrasi direncli ortostatik hipotansiyon gelisen 21 yasinda bir erkek olgu sunuldu. Olgu mineralokortikoid tedavisi ile kuadriseps ve tibialis anterior kaslarina elektriksel stimulasyon ile tedavi edildi. Bu tedavinin sonuclari ve ortostatik hipotansiyonun tedavi stratejileri literatur verileri isiginda tartisildi. Anahtar sozcukler: Servikal spinal kord yaralanmasi; ortostatik hipotansiyon; tedavi.