Unutkanlik soru

Merhaba Delta Cognimax Sitikolin+vitamin B6+ Vitamin B12 + folik asit preparatı. Yapılan tetkikle eksikliği tayin edilmemiş birisine vitaminin takviye edilmesini önermem. İkincisi, "Sitikolin"in her ne kadar kolinerjik dopaminerjik antioksidan antienflamatuar nöroprotektif etki gösterdiği belirtilse de halen kanıt düzeyi yeterli bir etkinlik göstermediği kanaatindeyim. Sağlıklı günler 1. Gareri, P., Castagna, A., Cotroneo, A. M., Putignano, S., De Sarro, G., & Bruni, A. C. (2015). The role of citicoline in cognitive impairment: pharmacological characteristics, possible advantages, and doubts for an old drug with new perspectives. Clinical interventions in aging, 10, 1421–1429. https://doi.org/*** *** **/CIA.S*** *** **. Dávalos A, Alvarez-Sabín J, Castillo J, Díez-Tejedor E, Ferro J, Martínez-Vila E, Serena J, Segura T, Cruz VT, Masjuan J, Cobo E, Secades JJ; International Citicoline Trial on acUte Stroke (ICTUS) trial investigators. Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial). Lancet. 2012 Jul 28;*** *** **):*** *** **. doi: *** *** **/S*** *** **(*** *** **. Epub 2012 Jun 11. PMID: *** *** **. 3. Zafonte RD, Bagiella E, Ansel BM, Novack TA, Friedewald WT, Hesdorffer DC, Timmons SD, Jallo J, Eisenberg H, Hart T, Ricker JH, Diaz-Arrastia R, Merchant RE, Temkin NR, Melton S, Dikmen SS. Effect of citicoline on functional and cognitive status among patients with traumatic brain injury: Citicoline Brain Injury Treatment Trial (COBRIT). JAMA. 2012 Nov 21;308(19):*** *** **. doi: *** *** **/jama.*** *** **. PMID: *** *** **.