Prognostic value of CHA2DS2-VASc score in patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention

Objectives The aim of the study was to investigate the relationship between CHA2DS2-VASc score and in-hospital and long-term all-cause and cardiovascular mortality in patients with STEMI who underwent primary PCI. Methods In this retrospective study, 604 patients, admitted to the emergency department with a diagnosis of STEMI, were included. The study patients were divided into three risk groups according to CHA2DS2-VASc score: low-risk group (1 point), moderate-risk group (2 points), and high-risk group (3 points and higher), respectively. Results The mean follow-up time was 680±286 days. In the high-risk group, the rates of in-hospital and long-term all-cause and cardiovascular mortality were higher than in the other groups. The Kaplan-Meier curves for the group with CHA2DS2-VASc scores >2 indicated a significantly shorter long-term survival (P<0.001). In the receiver operating characteristic curve analysis, CHA2DS2-VASc scores >2 were identified as an effective predictive cut-off point for all-cause mortality in STEMI (area under curve=0.850, 95% confidence interval: 0.819–0.878, P<0.001). CHA2DS2-VASc score >2 yielded a sensitivity of 70.18% and a specificity of 83%. Conclusion The CHA2DS2-VASc is a simple and easily calculated score that provides an additional level of risk stratification beyond that provided by conventional risk scores in predicting in-hospital and long-term all-cause and cardiovascular mortality in STEMI