Intermittent negative pressure wound therapy with instillation for the treatment of persistent periprosthetic hip infections: a report of two cases Mehmet Salih Söylemez 1, Korhan Özkan 2, Bülent Kılıç 3, Samet Erinç 4
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Intermittent negative pressure wound therapy with instillation (NPWTi) is increasingly utilized for the successful management of early periprosthetic infections in endoprostheses. While its efficacy in early-stage cases is well-documented, clinical literature regarding the application of intermittent NPWTi for late persistent periprosthetic infections of the hip remains limited. This study aims to contribute to the field by detailing the outcomes of this specific intervention.
Management of Late Persistent Periprosthetic Hip Infections
In this clinical report, we evaluate two specific cases involving patients who underwent multiple rounds of radical wound debridement to address late persistent periprosthetic infections of the hip. To optimize the healing process and control the infection, intermittent NPWTi was integrated into the surgical treatment protocol for both patients. This approach focuses on enhancing wound bed preparation through controlled negative pressure and solution instillation.
Clinical Outcomes and Follow-up Results
The therapeutic intervention involving intermittent NPWTi yielded successful clinical outcomes in both reported cases. Long-term monitoring was conducted to ensure the stability of the results and the absence of infection recurrence. The follow-up data is summarized below:
- Case 1: Successful treatment with no recurrence observed after a 3-year follow-up period.
- Case 2: Successful treatment with no recurrence observed after a 1-year follow-up period.
These results demonstrate that intermittent NPWTi can be an effective component in the complex management of late-stage persistent infections following hip endoprosthesis surgery.
